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1-Naphthoyl Chloride CAS 879-18-5

Chemical Name:1-Naphthoyl chloride
CAS Number:879-18-5
Molecular Formula:C11H7ClO
Molecular Weight:190.63 g/mol
Appearance:White to almost white powder

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With CAS 879-18-5, 1-naphthoyl chloride is an organic chemical of the class of aromatic acyl chlorides. It is a fundamental intermediate in chemical synthesis, especially helpful for adding the naphthoyl group into other compounds. The reactivity and adaptability of this chemical make it extensively used in the dye, agrochemical, and pharmaceutical sectors.

CAS 879-18-5 Chemical & Physical Properties

  • Chemical Formula: C11H7ClO
  • Molecular Weight:63 g/mol
  • Appearance: Pale yellow to white crystalline solid
  • Boiling Point:307 °C (585 °F) at 760 mmHg
  • Melting Point:37-40 °C (98-104 °F)
  • Density:271 g/cm³ at 25 °C (77 °F)
  • Flash Point:126 °C (259 °F)
  • Solubility: Reacts with water; soluble in organic solvents such as dichloromethane, chloroform, and benzene

1-Naphthoyl Chloride Application

Because of its reactivity and capacity to introduce the naphthoyl functional group, 1-naphthoyl chloride finds use in many different sectors:

Pharmaceuticals:

  • Intermediate in Drug Synthesis: Many medications are synthesized using CAS 879-18-5 as building blocks. It helps the naphthoyl moiety—a crucial component in several therapeutic molecules—to be introduced.
  • Active Pharmaceutical Ingredients (APIs): CAS 879-18-5 helps create APIs for drugs aimed at various conditions.

Agrochemicals:

  • Pesticides and Herbicides: Pesticides and herbicides among other agrochemical chemicals are synthesized using 1-naphthoyl chloride. The naphthoyl group can improve the stability and biological activity of some molecules.

Dye and Pigment Industry:

  • Colorants: CAS 879–18–5 acts as a precursor for dyes and pigments' synthesis. The color qualities and solubility of the resultant products might be affected by the naphthoyl group introduction.
  • Synthetic Dyes: CAS 879-18-5 is used in the manufacture of synthetic dyes that are applied in textiles, inks, and coatings.

Organic Synthesis:

  • Acylation Reagent: In organic synthesis, 1-naphthoyl chloride is used as an acylation reagent, introducing the naphthoyl group into different substrates.
  • Laboratory Reagent: 1-naphthoyl chloride is commonly utilized in research environments to investigate fresh synthetic routes and create new chemicals.

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